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Peak plasma concentrations are obtained about hours after ingestion of Li-Liquid. Lithium is reported to have a plasma half life of about 7 to 20 hours during the daytime. Lithium is excreted by the kidneys. There is a narrow margin between the therapeutic and the toxic plasma concentration. Therefore, not only is individual titration of lithium dosage essential to ensure constant plasma concentrations for the patient involved, but the conditions under which the blood samples are taken for monitoring must be carefully controlled. In practice a blood sample drawn 12 hours after the last dose of lithium in a patient who has been taking his daily lithium requirement at the scheduled hours during the past 48 hours is measured. Under such conditions the usual therapeutic plasma concentrations of lithium are - mmol/L, with a reported effective range of - /L