-Initial dose: Take one capsule of the lowest dose (phentermine mg/topiramate 23 mg extended-release) orally once a day in the morning for the first 14 days.
-Maintenance dose: After 14 days, take one capsule of the recommended dose (phentermine mg/topiramate 46 mg extended-release) orally once a day in the morning.
-Weight loss should be evaluated after 12 weeks with phentermine mg/topiramate 46 mg extended-release. If a patient has not lost at least 3% of baseline body weight, treatment discontinuation or dose escalation should be considered as it is unlikely the patient will achieve and sustain clinically meaningful weight loss at this dose.
Use: Adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in patients with an initial body mass index (BMI) of 30 kg/m2 or greater (obese) OR 27 kg/m2 or greater (overweight) in the presence of at least one weight-related comorbidity such as hypertension, type 2 diabetes mellitus, or dyslipidemia.
It has some mild side effects associated with it as well. Side effects occur when you take it for a very long period of time and in more quantity. Major drawback of Anavar is that it is too costly, although available in black market but one cannot be so sure of the authenticity of it bought from there. As it is DHT and due to this hair loss and acne can occur. But hair loss only in men who have got this hair loss disease genetically transmitted. There could be high blood pressure and high cholesterol levels but only for those who are not living a healthy life style and these diseases are not transmitted genetically to the users as well. Due to the non aromatizing nature of Anavar it has taken side effects of water retention and Gynecomastia out of the equation.