Anabolic steroids are synthetic derivatives of testosterone, the male sex hormone. They were in the 2nd World War and were originally developed to allow weakened and malnourished prisoners of war better recovery. They were also used for their protein anabolic effect of the disease of consumption and muscle atrophy and as a remedy for anemia. Very soon, they also found application in sports where they were administered as an illegal drug to improve performance in healthy athletes. In medicine, anabolic steroids are still in a failure of the testes (lack of own body education testosterone), growth in the event of failure or physical weakness (eg the elderly) use. They usually belong to the group of anabolic steroids.
Steroids (derived from the name of the first known steroids, cholesterol) and "like" suffix oeides) are a class of lipids (molecules with lipophilic groups generally insoluble in water). Steroids are derivatives of sterane hydrocarbons (cyclopentanoperhydrophenanthrene). Natural steroids are found in animals, plants and fungi, and many are synthesized in the smooth endoplasmic reticulum. Their biochemical functions ranging from vitamins and sex hormones (androgens and estrogens in men in women) on bile acid and toad poison for heart-active toxins of digitalis and oleander.
In animals and humans is the main steroid is cholesterol; plants contain it are not. Lipoprotein cholesterol and steroid hormones constituted such as adrenal cortical hormones (corticosteroids). Artificial derivatives of testosterone, the male sex hormone, anabolic steroids are used as bodybuilding products. This is a public interest in sports known as doping agents.
Because weight loss typically consists of both fat and lean tissue, measurement of body composition for diagnostic purposes, although potentially useful, is not essential. Although several early studies demonstrated that mortality is related not just to loss of weight but also to depletion of lean tissue, a recent study performed in patients on ART suggested that weight loss was a better predictor of mortality than lean or fat tissue measured by bioelectric impedance.( 13 ) Nonetheless, there has been considerable interest in the measurement of body composition in patients with HIV infection, and such measurements can be useful in conjunction with well-maintained weight records to characterize an individual's response to various medical or nutritional interventions.
Valproic acid was first synthesized in 1882 by Beverly S. Burton as an analogue of valeric acid , found naturally in valerian .  Valproic acid is a carboxylic acid , a clear liquid at room temperature. For many decades, its only use was in laboratories as a "metabolically inert" solvent for organic compounds. In 1962, the French researcher Pierre Eymard serendipitously discovered the anticonvulsant properties of valproic acid while using it as a vehicle for a number of other compounds that were being screened for antiseizure activity. He found it prevented pentylenetetrazol -induced convulsions in laboratory rats .  It was approved as an antiepileptic drug in 1967 in France and has become the most widely prescribed antiepileptic drug worldwide.  Valproic acid has also been used for migraine prophylaxis and bipolar disorder.