Although clearly not as effective as mechanical blood doping, or even the newer practice of erythropoietin injections, anabolic/androgenic steroids still do enhance Red Blood Cell concentrations. Whether or not this will consistently equate into an increase in aerobic capacity in healthy athletes remains a matter of speculation and debate, however their base effect on the process of erythropoiesis does not. Since bodybuilders are rarely concerned with things such as overall oxygen uptake capacity and optimal aerobic performance, no doubt this debate is not of tremendous interest to the average reader. Perhaps of greater interest though is the simple understanding of the mechanism involved in erythropoiesis, and how anabolic steroids interact with this process. I hope also evident through this piece is the more primary focus on the different agents, and the fact that the enhancement of red blood cell production is a trait shared by all anabolic/androgenic steroids. Certainly those mentions of the vast superiority of one agent such as Anadrol or Equipoise over all others should be ignored.
Anticoagulants: Patients on anticoagulants such as warfarin should be carefully monitored during anabolic steroid therapy as anabolic steroids may increase sensitivity to oral anticoagulants which may require a concomitant reduction in anticoagulant dosage to achieve a desirable prothrombin time (PT). Anticoagulant patients should be monitored regularly during anabolic steroid therapy, particularly during initiation and termination of therapy. Warfarin patients should have INR and PT monitored throughout androgen therapy and warfarin dosages titrated to achieve the desired INR and PT. Such patients should be monitored for occult bleeding.
Glucocorticoids are a class of corticosteroids that affect the metabolism of carbohydrates , fat , and proteins , and regulate glycogen and blood pressure possess pronounced anti-inflammatory activity and cause alteration of connective tissue in response to injuries. The anti-inflammatory and connective tissue effects of glucocorticoids might mask injuries, leading to more serious injuries to athletes. Because of this and metabolic regulation effects, the administration of any glucorticoid orally, rectally, intraveniously, or intramuscularly is prohibited and requires a therapeutic use exemption. Topical uses of glucocorticoids does not require an exemption.